Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review
Identifieur interne : 000937 ( Main/Exploration ); précédent : 000936; suivant : 000938Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review
Auteurs : Katherine M. Stiff [États-Unis] ; Philip R. Cohen [États-Unis]Source :
- Dermatology and Therapy [ 2193-8210 ] ; 2016.
Abstract
Verruciform xanthoma is a wart-like benign lesion. The classic histologic appearance consists of foamy histiocytes within elongated dermal papillae and epithelial acanthosis. The lesion most commonly occurs in the oral cavity, but has been reported in extra-oral sites such as the penis, scrotum, and vulva. The clinical and histologic characteristics of verruciform genital-associated (Vegas) xanthomas of the penis, scrotum, and vulva are reviewed.
PubMed was used to search the following term: verruciform xanthoma. The relevant papers were obtained and reviewed.
There have been 193 cases of genital-associated verruciform xanthomas. There were 164 in men and 29 in women. Similar to verruciform xanthomas of the oral mucosa, they presented as asymptomatic lesions, demonstrated foam cells in the dermal papillae, and were typically managed successfully with surgical excision.
Verruciform xanthoma is a benign lesion characterized by a wart-like growth that is most commonly seen in the oral mucosa. Verruciform xanthomas of the genital region have been coined Vegas xanthomas. Vegas xanthomas have been reported in association with a variety of diseases, as well as in healthy individuals. Biopsy is required for diagnosis, and complete surgical excision is typically curative.
Url:
DOI: 10.1007/s13555-016-0155-0
PubMed: 27848170
PubMed Central: 5336425
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review</title><author><name sortKey="Stiff, Katherine M" sort="Stiff, Katherine M" uniqKey="Stiff K" first="Katherine M." last="Stiff">Katherine M. Stiff</name><affiliation wicri:level="2"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0459 7529</institution-id><institution-id institution-id-type="GRID">grid.261103.7</institution-id><institution></institution><institution>Northeast Ohio Medical University,</institution></institution-wrap>Rootstown, OH USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Rootstown</wicri:cityArea></affiliation></author><author><name sortKey="Cohen, Philip R" sort="Cohen, Philip R" uniqKey="Cohen P" first="Philip R." last="Cohen">Philip R. Cohen</name><affiliation wicri:level="2"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2107 4242</institution-id><institution-id institution-id-type="GRID">grid.266100.3</institution-id><institution>Department of Dermatology,</institution><institution>University of California San Diego,</institution></institution-wrap>La Jolla, CA USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>La Jolla</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27848170</idno><idno type="pmc">5336425</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336425</idno><idno type="RBID">PMC:5336425</idno><idno type="doi">10.1007/s13555-016-0155-0</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000F38</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000F38</idno><idno type="wicri:Area/Pmc/Curation">000F37</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000F37</idno><idno type="wicri:Area/Pmc/Checkpoint">000481</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000481</idno><idno type="wicri:Area/Ncbi/Merge">008A07</idno><idno type="wicri:Area/Ncbi/Curation">008A07</idno><idno type="wicri:Area/Ncbi/Checkpoint">008A07</idno><idno type="wicri:doubleKey">2193-8210:2016:Stiff K:vegas:verruciform:genital</idno><idno type="wicri:Area/Main/Merge">000938</idno><idno type="wicri:Area/Main/Curation">000937</idno><idno type="wicri:Area/Main/Exploration">000937</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review</title><author><name sortKey="Stiff, Katherine M" sort="Stiff, Katherine M" uniqKey="Stiff K" first="Katherine M." last="Stiff">Katherine M. Stiff</name><affiliation wicri:level="2"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0459 7529</institution-id><institution-id institution-id-type="GRID">grid.261103.7</institution-id><institution></institution><institution>Northeast Ohio Medical University,</institution></institution-wrap>Rootstown, OH USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Rootstown</wicri:cityArea></affiliation></author><author><name sortKey="Cohen, Philip R" sort="Cohen, Philip R" uniqKey="Cohen P" first="Philip R." last="Cohen">Philip R. Cohen</name><affiliation wicri:level="2"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2107 4242</institution-id><institution-id institution-id-type="GRID">grid.266100.3</institution-id><institution>Department of Dermatology,</institution><institution>University of California San Diego,</institution></institution-wrap>La Jolla, CA USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>La Jolla</wicri:cityArea></affiliation></author></analytic><series><title level="j">Dermatology and Therapy</title><idno type="ISSN">2193-8210</idno><idno type="eISSN">2190-9172</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p>Verruciform xanthoma is a wart-like benign lesion. The classic histologic appearance consists of foamy histiocytes within elongated dermal papillae and epithelial acanthosis. The lesion most commonly occurs in the oral cavity, but has been reported in extra-oral sites such as the penis, scrotum, and vulva. The clinical and histologic characteristics of verruciform genital-associated (Vegas) xanthomas of the penis, scrotum, and vulva are reviewed.</p></sec><sec><title>Methods</title><p>PubMed was used to search the following term: verruciform xanthoma. The relevant papers were obtained and reviewed.</p></sec><sec><title>Results</title><p>There have been 193 cases of genital-associated verruciform xanthomas. There were 164 in men and 29 in women. Similar to verruciform xanthomas of the oral mucosa, they presented as asymptomatic lesions, demonstrated foam cells in the dermal papillae, and were typically managed successfully with surgical excision.</p></sec><sec><title>Conclusion</title><p>Verruciform xanthoma is a benign lesion characterized by a wart-like growth that is most commonly seen in the oral mucosa. Verruciform xanthomas of the genital region have been coined Vegas xanthomas. Vegas xanthomas have been reported in association with a variety of diseases, as well as in healthy individuals. 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Nikai</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Ohio</li></region></list><tree><country name="États-Unis"><region name="Ohio"><name sortKey="Stiff, Katherine M" sort="Stiff, Katherine M" uniqKey="Stiff K" first="Katherine M." last="Stiff">Katherine M. 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